DeepMind: A Quest for a Cure: AI Drug Design with Isomorphic Labs

Author: Google DeepMind - Bewertung: 28x - Views:217

In this episode, host Hannah Fry is joined by Max Jaderberg and Rebecca Paul of Isomorphic Labs to explore the future of drug discovery in the age of AI. They discuss how new technology, particularly AlphaFold 3, is revolutionizing the field by predicting the structure of life’s molecules, paving the way for faster and more efficient drug discovery.



They dig into the immense complexities of designing new drugs: How do you find the right molecular key for the right biological lock? How can AI help scientists understand disease better and overcome challenges like drug toxicity? And what about the diseases that are currently considered “undruggable”? Finally, they explore the ultimate impact of this technology, from the future of personalized medicine to the ambitious goal of being able to eventually design treatments for all diseases.



Further reading:



AlphaFold 3: https://www.nature.com/articles/s41586-024-07487-w

AlphaFold Server: https://alphafoldserver.com/

Isomorphic Labs: https://www.isomorphiclabs.com/

AlphaFold 3 code and weights: https://github.com/google-deepmind/alphafold3



Timecodes:

00:00 Intro

02:11 AI & Disease

05:30 AI in Biology

06:51 Molecules and Proteins

12:05 AlphaFold 3

14:40 Demo

16:20 Human-AI collaboration

24:30 Drug Design Challenges

39:00 Beyond Animal Models

44:35 AI Drug Future

46:30 Outro



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Thanks to everyone who made this possible, including but not limited to:



Presenter: Professor Hannah Fry

Series Producer: Dan Hardoon

Editor: Rami Tzabar

Commissioner & Producer: Emma Yousif

Music composition: Eleni Shaw

Audio engineer: Richard Courtice



Production Manager: Dan Lazard

Studio Manager: Nicholas Duke

Video Director: Bernardo Resende

Video Editor: Bilal Merhi

Audio Engineer: Perry Rogantin

Camera and Lighting Operator: Robert Messere

Production Coordination: Zoey Roberts, Sarah Ellen Morton

Visual Identity and Design: Rob Ashley

Commissioned by Google DeepMind



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