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Diets low in carbs and fibre alters gut microbes and drives the growth of colon polyps causing colorectal cancer.

Study uncovers how low-carb diet drives colorectal cancer development | Temerty Faculty of Medicine U of T researchers have shown how a low carbohydrate diet can worsen the DNA-damaging effects of some…

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Study uncovers how low-carb diet drives colorectal cancer development | Temerty Faculty of Medicine



U of T researchers have shown how a low carbohydrate diet can worsen the DNA-damaging effects of some gut microbes to cause colorectal cancer. The study compared the effects of three different diets in combination with specific gut bacteria on colorectal cancer development in mice.



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Researchers at the University of Toronto found that pairing a low-carb, low-fibre diet with a strain of E. coli that makes the DNA-damaging toxin colibactin sparks polyp formation (and ultimately colorectal cancer) in mice—something that didn’t happen on a normal or Western-style diet. The low-fibre mix stokes gut inflammation and thins the mucus barrier, giving colibactin free rein to damage colon cells, especially in animals already hampered by DNA-repair mutations.



Beyond warning keto-style dieters of this hidden risk, the team is exploring fibre supplements (like inulin) and targeted antibiotics to knock out colibactin-producers. They’re also looking at whether common probiotic E. coli strains pose a threat for folks with Lynch syndrome or other high-risk profiles—and dreaming up human studies that could one day help prevent diet-driven colorectal cancer.

1. Sofort-Triage & Abwehrmaßnahmen

SOC Incident Playbook: Vulnerability Remediation & Verification
Syntax validiert (0 Fehler)
title: Detect Exploitation - Diets low in carbs and fibre alters gut microbes and drives the growth of colon polyps causing colorectal cancer.
id: e410ac90-b875-4583-8b42-b801bb6d36d5
status: experimental
description: Automatisch generierte SIEM-Erkennungsregel basierend auf CTI Intelligence
references:
  - https://tsecurity.de/
author: iShareStuff CTI Automated Detection Engine
date: 2026-09-27
logsource:
  category: network_connection
  product: any
detection:
  selection:
      CommandLine|contains:
        - 'exploit'
  condition: selection
falsepositives:
  - Legitime administrative Zugriffe oder Penetrationstests
level: high
tags:
  - attack.initial_access
Syntax validiert (0 Fehler)
rule CTI_Threat_Indicator {
    meta:
        author = "iShareStuff CTI Automated Detection Engine"
        date = "2026-09-27"
        description = "YARA Signature for "
    strings:
        $str = "Diets low in carbs and fibre a" ascii wide
    condition:
        any of them
}
Syntax validiert (0 Fehler)
index=security sourcetype IN ("cisco:asa", "pan:traffic", "zeek_conn", "suricata", "WinEventLog:Security")
("Diets low in carbs and fibre alters gut ")
| stats count earliest(_time) as first_seen latest(_time) as last_seen by src_ip, dest_ip, dest_host, signature
| eval first_seen=strftime(first_seen, "%Y-%m-%d %H:%M:%S"), last_seen=strftime(last_seen, "%Y-%m-%d %H:%M:%S")
| sort - count
Syntax validiert (0 Fehler)
message: "*Diets low in carbs and fibre alters gut *"
Syntax validiert (0 Fehler)
CommonSecurityLog
| where Message has "Diets low in carbs and fibre alters gut "
| summarize EventCount = count(), FirstSeen = min(TimeGenerated), LastSeen = max(TimeGenerated) by SourceIP, DestinationIP, DestinationPort, Activity
| extend DetectionRule = "iShareStuff-CTI-Compiled"
| sort by EventCount desc

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Resource Development
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Initial Access
Execution
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Command and Control
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Impact
tsecurity.de Cognitive Threat RAG
Fokus-Vektor:

Analyse für identifizierte Bedrohung auf Basis von Live-CTI (ENISA EUVD): CVSS 0.0 · EPSS 0.0% · CISA KEV: nein. Handlungsableitung aus den verlinkten Hersteller-Quellen.

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⚡ Empfohlene Sofortmaßnahmen
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Thematisch verwandte Begriffe: Diets, carbs, fibre, alters · 6 Treffer

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