Is there a "rosetta for linux"?

I know things like Wine, proton compatibility layer, etc. exist for linux, but idk how broadly they work (like is proton just for games?). I want to know if there any relatively straightforward way to set up something that will work like MacOS rosetta, so that once it's set up I can just run anything made for windows even if there's a performance difference, that I just guarantee it will be ABLE to run? I'm okay with messing around the first time I set up the OS, but having to do that whenever I want to check out a new app or play around with some tool like COLMAP for vfx is a dealbreaker for me. Is there a way I can do this?