Claude designs proteins that bind in the lab

Claude designed new proteins from scratch, and the lab confirmed they work. Given a target and 24 hours on its own, it generated, folded, and scored them using open-source biomolecular models, checked their diversity and novelty with bioinformatics tools, and chose the designs most likely to grip the target. Those designs were then made and measured by two independent labs, Adaptyv Bio and GenScript. Across the 12 targets shown, nearly half of Claude's designs bound, and most targets got a high-affinity binder.

What you're watching: A co-folding diffusion trajectory rendered by Claude for a validated binder against each of 12 targets. Every protein on screen is one confirmed to bind experimentally.